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Fabgennix
Phospholipase A2 Polyclonal Antibody
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产品信息
PLAP2-212AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 450-500 on human Phospholipase A2-activating protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Phospholipase A2 catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Group IB phospholipase A2; MGC119834; MGC119835; Phosphatidylcholine 2-acylhydrolase 1B; Phospholipase A2; phospholipase A2, group IB (pancreas); unnamed protein product
基因别名: PLA2; PLA2A; PLA2G1B; PPLA2
UniProt ID: (Bovine) P00593, (Human) P04054
Entrez Gene ID: (Bovine) 282457, (Human) 5319
innate immune response in mucosa
lipid catabolic process
antibacterial humoral response
phosphatidylcholine metabolic process
phosphatidylglycerol metabolic process
arachidonic acid secretion
defense response to Gram-positive bacterium
antimicrobial humoral immune response mediated by antimicrobial peptide
positive regulation of glomerular visceral epithelial cell apoptotic process
activation of MAPK activity
neutrophil mediated immunity
fatty acid biosynthetic process
phosphatidic acid biosynthetic process
actin filament organization
signal transduction
positive regulation of calcium ion transport into cytosol
glucose transport
leukotriene biosynthetic process
neutrophil chemotaxis
activation of phospholipase A2 activity
interleukin-8 production
cellular response to insulin stimulus
intracellular signal transduction
phosphatidylglycerol acyl-chain remodeling
phosphatidylinositol acyl-chain remodeling
phosphatidylserine acyl-chain remodeling
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
multicellular organism lipid catabolic process
positive regulation of DNA replication
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
positive regulation of protein secretion
positive regulation of immune response
positive regulation of NF-kappaB transcription factor activity
