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Invitrogen
RCCD1 Polyclonal Antibody
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产品信息
PA5-59294
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PFIAVQPFPA LLDLPMGSDA VKASCGSRHT AVVTRTGELY TWGWGKYGQL GHEDTTSLDR PRRVEYFVDK QLQVKAVTCG PWNTYVYAVE KG
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 85%.
靶标信息
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 (PubMed:24981860). Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation (PubMed:24981860). Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8 (PubMed:28455245).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RCC1 domain-containing protein 1
基因别名: RCCD1
UniProt ID: (Human) A6NED2
Entrez Gene ID: (Human) 91433
