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Invitrogen
RNF149 Polyclonal Antibody
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产品信息
PA5-110306
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 221-400 of human RNF149 (NP_775918.2).
偶联物
形式
Liquid
浓度
1.17 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FYYIQRFLYT GSQIGSQSHR KETKKVIGQL LLHTVKHGEK GIDVDAENCA VCIENFKVKD IIRILPCKHI FHRICIDPWL LDHRTCPMCK LDVIKALGYW GEPGDVQEMP APESPPGRDP AANLSLALPD DDGSDDSSPP SASPAESEPQ CDPSFKGDAG ENTALLEAGR SDSRHGGPIS
靶标信息
RNF149 is a E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA polymerase-transactivated protein 2; E3 ubiquitin-protein ligase RNF149; Goliath-related E3 ubiquitin-protein ligase 4; RING finger protein 149; RING-type E3 ubiquitin transferase RNF149
基因别名: 1600023E10Rik; AV037261; C76763; DNAPTP2; Gm15832; Greul4; OTTMUSG00000026591; RNF149
UniProt ID: (Human) Q8NC42, (Mouse) Q3U2C5
Entrez Gene ID: (Human) 284996, (Mouse) 67702
zinc ion binding
ligase activity
ubiquitin protein ligase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
