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Invitrogen
RPL11 Polyclonal Antibody
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产品信息
PA5-34604
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Zebrafish
已发表种属
C. elegans,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human RPL11.
偶联物
形式
Liquid
浓度
0.9 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Heat mediated antigen retrieval recommended prior to tissue staining.
This antibody is predicted to react with mouse, rat, cow, cat and orangutan based on sequence homology.
靶标信息
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 60S ribosomal protein L11; cell growth-inhibiting protein 34; CLL-associated antigen KW-12; Large ribosomal subunit protein uL5; RP11-223J15.3
基因别名: DBA7; GIG34; L11; RPL11; zgc:86748
UniProt ID: (Human) P62913
Entrez Gene ID: (Human) 6135, (Zebrafish) 415229
ribosomal large subunit assembly
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
rRNA processing
translation
translational initiation
protein targeting
SRP-dependent cotranslational protein targeting to membrane
viral transcription
protein localization to nucleus
ribosomal large subunit biogenesis
apoptotic process
hemopoiesis
erythrocyte differentiation
hemoglobin biosynthetic process
glucose homeostasis
chordate embryonic development
regulation of innate immune response
erythrocyte development
