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Invitrogen
RTN4RL2 Polyclonal Antibody
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产品信息
PA5-34488
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
An 18 amino acid peptide near the carboxy terminus of human RTN4RL2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is rat brain tissue lysate.
PA5-34488 can be used with blocking peptide PEP-1530.
靶标信息
Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NgR2; Nogo receptor-like 3; Nogo-66 receptor homolog 1; Nogo-66 receptor-related protein 2; Reticulon-4 receptor-like 2; RTN4RL2; rtn4rl2 {ECO:0000312|RGD:727797}
基因别名: NgR2; NGRH1; NGRL3; RTN4RL2
UniProt ID: (Human) Q86UN3, (Rat) Q80WD1
Entrez Gene ID: (Human) 349667, (Rat) 311169
