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Immunogen sequence: MKIEEVKSTT KTQRIASHSH VKGLGLDESG LAKQAASGLV GQENAREACG VIVELIKSKK MAGRAVLLAG PPGTGKTALA LAIAQELGSK VPFCPMVGSE VYSTEIKKTE VLMENFRRAI GLRIKETKEV YEGEVTELTP CETENPMGGY GKTISHVIIG LKTAKGTKQL KLDPSIFESL QKERVEAGDV IYIEANSGAV KRQGRCDTYA TEFD; Positive Samples: MCF-7, HeLa, 293T, Mouse testis, Mouse spleen, Rat testis; Cellular Location: Cytoplasm, Membrane, Nucleus, Nucleus matrix, centrosome, cytoskeleton, microtubule organizing center, nucleoplasm
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; DNA helicase p50; ECP-54; INO80 complex subunit H; NMP 238; Nuclear matrix protein 238; Pontin 52; RuvB (E coli homolog)-like 1; RuvB-like 1; RuvB-like AAA ATPase 1; RuvB-like protein 1; TAP54-alpha; TATA binding protein interacting protein 49 kDa; TIP49a; TIP60-a; TIP60-associated protein 54-alpha
基因别名: 2510009G06Rik; ECP-54; ECP54; INO80H; NMP 238; NMP238; PONTIN; Pontin52; RUVBL1; RVB1; TIH1; TIP49; TIP49A
UniProt ID: (Human) Q9Y265, (Rat) P60123, (Mouse) P60122
Entrez Gene ID: (Human) 8607, (Rat) 65137, (Mouse) 56505