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Invitrogen

RhoA/RhoB/RhoC Recombinant Rabbit Monoclonal Antibody (5E6)

查看其他5个RhoA/RhoB/RhoC抗体

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产品信息

MA572483

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:1,000-1:2,000
-

免疫组化（石蜡） (IHC (P))

1:100-1:500
-

免疫组化（冰冻） (IHC (F))

1:100-1:500
-

免疫细胞化学 (ICC/IF)

1:50-1:200
-

流式细胞分析 (Flow)

1:50-1:100
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

5E6

抗原

KLH conjugated synthetic peptide derived from human RhoA.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

100 µg

纯化类型

Protein A

保存液

TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

RhoA is described as a small GTPase protein that regulates the actin cytoskeleton in the formation of stress fibers. RhoA is also included in the related proteins of the Ras superfamily, which involves proteins in the regulation and timing of cell division.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: aplysia ras-related homolog 9 (RhoC); aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; aplysia ras-related homolog B; h12; h6; h9; plysia ras-related homolog A2; Ras family member A; ras homolog 9 (RhoC); ras homolog A1; ras homolog A2; ras homolog B; ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member AB; ras homolog gene family, member B; ras homolog gene family, member C; Rho; Rho cDNA clone 12; Rho cDNA clone 6; Rho cDNA clone 9; Rho family GTPase; Rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; rhoB; SIG-61; Silica-induced gene 61 protein; Transforming protein RhoA

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基因别名: AA017882; AI324259; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; ARHB; ARHC; RHO12; RHOA; RHOB; RHOC

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UniProt ID: (Rat) P61589, (Mouse) Q9QUI0, (Rat) P62747, (Mouse) P62746, (Mouse) Q62159

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Entrez Gene ID: (Rat) 117273, (Mouse) 11848, (Rat) 64373, (Mouse) 11852, (Mouse) 11853, (Rat) 295342

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功能
GTPase activity protein binding GTP binding myosin binding GDP binding protein domain specific binding Rho GDP-dissociation inhibitor binding nucleotide binding signal transducer activity small GTPase
参与通路
cell morphogenesis response to hypoxia regulation of transcription from RNA polymerase II promoter cytoskeleton organization cell adhesion cell-matrix adhesion small GTPase mediated signal transduction skeletal muscle tissue development regulation of actin polymerization or depolymerization metabolic process response to mechanical stimulus response to glucose regulation of neuron projection development substantia nigra development cerebral cortex cell migration forebrain radial glial cell differentiation actin cytoskeleton organization cell differentiation positive regulation of cell growth regulation of cell migration positive regulation of cell migration androgen receptor signaling pathway positive regulation of actin filament polymerization stress-activated protein kinase signaling cascade positive regulation of cytokinesis negative regulation of intracellular steroid hormone receptor signaling pathway regulation of osteoblast proliferation cleavage furrow formation apolipoprotein A-I-mediated signaling pathway response to drug positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling stress fiber assembly response to amino acid positive regulation of cysteine-type endopeptidase activity involved in apoptotic process apical junction assembly negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process ossification involved in bone maturation wound healing, spreading of cells response to ethanol negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of translation positive regulation of cell adhesion positive regulation of vasoconstriction positive regulation of smooth muscle contraction neuron projection morphogenesis regulation of dendrite development negative chemotaxis response to glucocorticoid positive regulation of stress fiber assembly regulation of calcium ion transport negative regulation of cell death trabecula morphogenesis cellular response to progesterone stimulus positive regulation of podosome assembly mitotic spindle assembly skeletal muscle satellite cell migration regulation of neural precursor cell proliferation cell cycle integrin-mediated signaling pathway Rho protein signal transduction GTP metabolic process cell division positive regulation of lipase activity angiogenesis intracellular protein transport obsolete transformed cell apoptotic process endosome to lysosome transport positive regulation of apoptotic process positive regulation of angiogenesis negative regulation of cell cycle cellular response to hydrogen peroxide cellular response to ionizing radiation cytokinesis transport apoptotic process multicellular organism development protein transport signal transduction
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