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Invitrogen
SAMHD1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-73022
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SAMHD1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The amino acid sequence used as immunogen for this antibody is 100% homologous in Gibbon, Macaque, and 83% in Bovine, Equine, and Porcine.
靶标信息
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dendritic cell-derived IFNG-induced protein; dNTPase; IFN-gamma induced; interferon-gamma-inducible protein Mg11; monocyte protein 5; RP1-132F21.1; SAM domain and HD domain 1; SAM domain and HD domain, 1; SAM domain and HD domain-containing protein 1; unknown intracellular protein; unnamed protein product
基因别名: CHBL2; DCIP; E330031J07Rik; HDDC1; hSAMHD1; Mg11; MOP-5; mSAMHD1; SBBI88
UniProt ID: (Human) Q9Y3Z3, (Mouse) Q60710
Entrez Gene ID: (Human) 25939, (Mouse) 56045, (Rat) 311580
double-strand break repair via homologous recombination
dGTP catabolic process
immune response
cellular response to DNA damage stimulus
deoxyribonucleotide catabolic process
somatic hypermutation of immunoglobulin genes
regulation of innate immune response
dATP catabolic process
protein homotetramerization
defense response to virus
negative regulation of type I interferon-mediated signaling pathway
DNA strand resection involved in replication fork processing
modulation by host of viral RNA genome replication
positive regulation of transcription, DNA-templated
negative regulation of viral life cycle
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
