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Invitrogen
SARS-CoV-2 Delta Spike Protein RBD Chimeric Recombinant Human Monoclonal Antibody (D006)
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产品信息
MA5-60606
产品规格
种属反应
Virus
宿主/亚型
Human
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
D006
抗原
Recombinant SARS-CoV-2 Delta Spike ECD Protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Specifically recognize the SARS-CoV-2 Delta Spike RBD and ECD. No cross-reactivity with SARS-CoV-2 wild type, Alpha, Beta, Omicron BA.2.75 variant.. Has cross-reactivity in ELISA with: SARS-CoV-2 Delta (B.1.617.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Delta (B.1.617.2) Spike RBD Protein; No cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1.16) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1.5) Spike RBD Protein; SARS-CoV-2 Omicron (XBB.1.5) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB) Spike RBD Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BQ.1.1)Spike RBD Protein; SARS-CoV-2 Omicron (BF.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4.6/BF.7) Spike RBD Protein; SARS-CoV-2 Omicron (BA.4.6) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.3.20) Spike RBD Protein; SARS-CoV-2 Omicron (B.1.1.529) S1+S2 trimer Protein; SARS-CoV-2 Omicron (B.1.1.529) Spike RBD Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike RBD Protein; SARS-CoV-2 Beta (B.1.351) Spike S1+S2 trimer Protein; SARS-CoV-2 Beta (B.1.351, B.1.351.2, B.1.351.3) Spike RBD Protein; SARS-CoV-2 Spike S1+S2 (D614G) trimer Protein; SARS-CoV-2 Spike RBD Protein
靶标信息
The SARS-CoV-2 Delta Spike Protein RBD refers to the receptor-binding domain (RBD) of the spike (S) protein in the Delta variant of the SARS-CoV-2 virus, which is responsible for COVID-19. The RBD is a critical region within the S1 subunit of the spike protein that binds to the angiotensin-converting enzyme 2 (ACE2) receptor on human cells, facilitating viral entry. The Delta variant, first identified in India, possesses several mutations in the RBD that can enhance its binding affinity to the ACE2 receptor, potentially increasing the virus's transmissibility and partially evading immune responses. These mutations have significant implications for the effectiveness of vaccines and therapeutic antibodies, making it essential to monitor and adapt public health strategies accordingly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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