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Invitrogen
SCXA Polyclonal Antibody
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SCXA Antibody (PA5-23943) in IHC (P)
Immunohistochemistry analysis of SCXA in paraffin-embedded Human breast carcinoma tissue. Samples were incubated with SCXA polyclonal antibody (Product # PA5-23943) using a dilution of 1:100 for 1 hour at room temperature followed by undiluted CRF Anti-Polyvalent HRP Polymer antibody. Tissue was fixed with formaldehyde at room temperature. Heat induced epitope retrieval was performed by EDTA buffer (pH 9 0)... View More
产品信息
PA5-23943
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Chicken,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 172-201 amino acids from the C-terminal region of human SCXA
偶联物
形式
Liquid
浓度
0.32 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with chicken based on sequence homology.
靶标信息
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and bHLH transcription factor binding activity. Contributes to E-box binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Basic helix-loop-helix transcription factor scleraxis; bHLHa41; bHLHa48; Class A basic helix-loop-helix protein 41; Class A basic helix-loop-helix protein 48; class II bHLH protein scleraxis; scleraxis basic helix-loop-helix transcription factor; scleraxis homolog A; scleraxis homolog B
基因别名: BB114693; BHLHA41; BHLHA48; Scl; SCX; SCXA; SCXB
UniProt ID: (Human) Q7RTU7, (Mouse) Q64124
Entrez Gene ID: (Human) 642658, (Mouse) 20289
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
E-box binding
protein binding
protein dimerization activity
basic helix-loop-helix transcription factor
mesoderm formation
tissue homeostasis
endochondral ossification
chondrocyte differentiation
heart valve morphogenesis
heart valve formation
transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of gene expression
cell differentiation
collagen fibril organization
BMP signaling pathway
positive regulation of collagen biosynthetic process
skeletal muscle cell differentiation
tendon development
tendon cell differentiation
tendon formation
deltoid tuberosity development
negative regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system development
Sertoli cell differentiation
face morphogenesis
regulation of cartilage development
positive regulation of cartilage development
sclerotome development
cellular response to mechanical stimulus
cellular response to transforming growth factor beta stimulus
positive regulation of gastrulation
regulation of transcription, DNA-templated
multicellular organism development
cartilage development
