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Invitrogen
SCYL1 Polyclonal Antibody
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SCYL1 Antibody (PA5-93185) in WB
Western blot analysis of SCYL1 in extracts from wild type (WT) and SCYL1 knockout (KO) 293T(KO) cells. Samples were incubated with SCYL1 Polyclonal antibody (Product # PA5-93185) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-93185
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 460-740 of human SCYL1 (NP_0657313)
偶联物
形式
Liquid
浓度
1.92 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SASTRHRVLT SAFSRATRDP FAPSRVAGVL GFAATHNLYS MNDCAQKILP VLCGLTVDPE KSVRDQAFKA IRSFLSKLES VSEDPTQLEE VEKDVHAASS PGMGGAAASW AGWAVTGVSS LTSKLIRSHP TTAPTETNIP QRPTPEGVPA PAPTPVPATP TTSGHWETQE EDKDTAEDSS TADRWDDEDW GSLEQEAESV LAQQDDWSTG GQVSRASQVS NSDHKSSKSP ESDWSSWEAE GSWEQGWQEP SSQEPPPDGT RLASEYNWGG PESSDKGDPF A; Positive Samples: HeLa, Mouse pancreas; Cellular Location: Cytoplasm, Endoplasmic reticulum-Golgi intermediate compartment, Golgi apparatus, Nucleus, centrosome, cis-Golgi network, cytoskeleton, microtubule organizing center
靶标信息
With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 105 kDa kinase-like protein; Coated vesicle-associated kinase of 90 kDa; likely ortholog of mouse N-terminal kinase-like protein; Mitosis-associated kinase-like protein NTKL; N-terminal kinase-like protein; SCY1-like 1 splice variant 13; SCY1-like 1 splice variant 15; SCY1-like protein 1; SCY1-like, kinase-like 1; Telomerase regulation-associated protein; Telomerase transcriptional element-interacting factor; telomerase transcriptional elements-interacting factor; Teratoma-associated tyrosine kinase; ubiquitous protein kinase-like (105 kDa)
基因别名: 2810011O19Rik; C85140; CVAK90; GKLP; HT019; mdf; mfd; NKTL; NTKL; P105; SCAR21; SCYL1; TAPK; TEIF; TRAP
UniProt ID: (Human) Q96KG9, (Mouse) Q9EQC5, (Rat) Q5M9F8
Entrez Gene ID: (Human) 57410, (Mouse) 78891, (Rat) 293684
