Invitrogen

SEMA3C Polyclonal Antibody

Name: SEMA3C Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-103168

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1 篇参考文献

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说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)
已发表图片 (1)

SEMA3C Antibody in Immunocytochemistry (ICC/IF)

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SEMA3C Antibody (PA5-103168) in ICC/IF

Immunocytochemistry analysis of SEMA3C in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SEMA3C polyclonal antibody (Product # PA5-103168) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).

SEMA3C Antibody in Immunohistochemistry (IHC)

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Immunogen image

Immunogen Image SEMA3C Polyclonal Antibody

产品信息

PA5-103168

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:100-1:500

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human SEMA3C(Accession Q99985), corresponding to amino acid residues H716-S751.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2852538

产品详细信息

Antibody detects endogenous levels of total SEMA3C.

靶标信息

The SEMA3C gene encodes the protein semaphorin 3C, a member of the semaphorin family known for its roles in axonal guidance, cellular signaling, and vascular development. Semaphorin 3C is involved in guiding neurons during development by serving as a repulsive cue, helping establish proper neural network formation through interaction with neuropilin and plexin receptors. It also plays crucial roles in angiogenesis and cardiac development by influencing endothelial cell behavior and migration. In the context of cancer, SEMA3C is implicated in tumor progression, where its dysregulation can promote tumor cell invasion and metastasis by modifying the extracellular matrix and affecting cellular adhesion. Research has demonstrated that SEMA3C can alter the tumor microenvironment, making it a potential target for cancer therapies aimed at inhibiting metastasis and controlling tumor growth. Understanding SEMA3C's function in various biological processes continues, highlighting its significance in developmental biology and disease modulation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。