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Invitrogen
SERPINI2 Polyclonal Antibody
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产品信息
PA5-88240
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 56-405 of human SERPINI2 (NP_0062081)
偶联物
形式
Liquid
浓度
1.31 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LEMVQLGAKG KAQQQIRQTL KQQETSAGEE FFVLKSFFSA ISEKKQEFTF NLANALYLQE GFTVKEQYLH GNKEFFQSAI KLVDFQDAKA CAEMISTWVE RKTDGKIKDM FSGEEFGPLT RLVLVNAIYF KGDWKQKFRK EDTQLINFTK KNGSTVKIPM MKALLRTKYG YFSESSLNYQ VLELSYKGDE FSLIIILPAE GMDIEEVEKL ITAQQILKWL SEMQEEEVEI SLPRFKVEQK VDFKDVLYSL NITEIFSGGC DLSGITDSSE VYVSQVTQKV FFEINEDGSE AATSTGIHIP VIMSLAQSQF IANHPFLFIM KHNPTESILF MGRVTNPDTQ EIKGRDLDSL; Positive Samples: Mouse pancreas, Rat pancreas
靶标信息
The protein encoded by this gene is a member of the serine protease inhibitor superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: neuroserpin; pancreas-specific serpin; serine (or cysteine) peptidase inhibitor, clade I, member 2; Serine protease inhibitor 14; Serpin I2; serpin peptidase inhibitor, clade I, member 2; SERPIN12
基因别名: Serpini2; Spi14
UniProt ID: (Mouse) Q9JK88
Entrez Gene ID: (Rat) 171149, (Mouse) 67931
