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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Recommended positive controls: HeLa, Raw264.7, C2C12, Rat2.
Predicted reactivity: Mouse (94%), Rat (93%), Xenopus laevis (80%), Rhesus Monkey (98%), Chimpanzee (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Sestrin-3
基因别名: 5630400E15Rik; BC003348; Sesn3; SEST3
UniProt ID: (Mouse) Q9CYP7
Entrez Gene ID: (Rat) 315427, (Mouse) 75747