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Invitrogen
SEZ6L2 Polyclonal Antibody
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SEZ6L2 Antibody (PA5-47669) in IHC (F)
Immunohistochemical analysis of SEZ6L2 in immersion fixed frozen sections of mouse embryo (15 d.p.c.). Samples were incubated in SEZ6L2 polyclonal antibody (Product # PA5-47669) using a dilution of 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to developing brain (med... View More
产品信息
PA5-47669
产品规格
种属反应
Human,
Mouse
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse SEZ6L2/BSRP-A Leu28-Ser837
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs and Western blots, less than 5% cross–reactivity with recombinant mouse (rm) BSRP-B and rmBSRP-C is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
The SEZ6L2 gene encodes the protein seizure-related 6 homolog-like 2, which plays roles in neural development and synaptic function. SEZ6L2 is part of the SEZ6 protein family recognized for their participation in the formation and maintenance of neural connections. This protein is prominently expressed in the brain and is involved in the molecular processes underlying synaptic differentiation and dendritic growth, crucial for cognitive functions and neurodevelopment. SEZ6L2 interacts with other neural proteins to mediate signaling pathways that regulate the balance between excitation and inhibition in neural circuits, which is vital for proper neurological function and development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain-specific receptor-like protein A; BSRP-A; Seizure 6-like protein 2; seizure related 6 homolog (mouse)-like 2; seizure related 6 homolog-like 2; seizure related 6-like protein 2; type I transmembrane receptor (seizure-related protein)
基因别名: AI835913; AW121566; BSRP-A; BSRPA; PSK; PSK-1; Psk1; SEZ6L2; UNQ1903/PRO4349
UniProt ID: (Human) Q6UXD5, (Mouse) Q4V9Z5
Entrez Gene ID: (Human) 26470, (Mouse) 233878
