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Invitrogen
SF3B2 Polyclonal Antibody
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产品信息
PA5-96456
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 616-895 of human SF3B2 (NP_0068332)
偶联物
形式
Liquid
浓度
0.14 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SLGMPVGPNA HKVPPPWLIA MQRYGPPPSY PNLKIPGLNS PIPESCSFGY HAGGWGKPPV DETGKPLYGD VFGTNAAEFQ TKTEEEEIDR TPWGELEPSD EESSEEEEEE ESDEDKPDET GFITPADSGL ITPGGFSSVP AGMETPELIE LRKKKIEEAM DGSETPQLFT VLPEKRTATV GGAMMGSTHI YDMSTVMSRK GPAPELQGVE VALAPEELEL DPMAMTQKYE EHVREQQAQV EKEDFSDMVA EHAAKQKQKK RKAQPQDSRG GSKKYKEFKF; Positive Samples: HeLa, MCF7, SW620, A375, Mouse testis; Cellular Location: Nucleus
靶标信息
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: pre-mRNA splicing factor SF3b 145 kDa subunit; Pre-mRNA-splicing factor SF3b 145 kDa subunit; SAP 145; SF3b145; spliceosome associated protein 145; Spliceosome-associated protein 145; Splicing factor 3B subunit 2; splicing factor 3b, subunit 2, 145kD; splicing factor 3b, subunit 2, 145kDa
基因别名: 145kDa; 2610311M13Rik; 2810441F20Rik; B230398H18Rik; Cus1; SAP145; SF3b1; SF3B145; SF3b150; SF3B2
UniProt ID: (Human) Q13435, (Mouse) Q3UJB0
Entrez Gene ID: (Human) 10992, (Rat) 293671, (Mouse) 319322
