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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total SGCE.
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Epsilon sarcoglycan; Epsilon SG; Epsilon-sarcoglycan; epsilon-sarcoglycan {ECO:0000312|EMBL:AAO37579.1}; Epsilon-SG; epsilon-SG {ECO:0000250|UniProtKB:O43556}; sarcoglycan; sgce {ECO:0000312|EMBL:AAO37579.1, ECO:0000312|RGD:1303201}
基因别名: e-SG; ESG; SGCE; UNQ433/PRO840
UniProt ID: (Mouse) O70258, (Rat) Q6YAT4
Entrez Gene ID: (Mouse) 20392, (Rat) 432360