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Invitrogen
SHC3 Polyclonal Antibody
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产品信息
PA5-106262
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SHC3(Accession Q92529), corresponding to amino acid residues L398-K448.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Shc3.
靶标信息
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: N-Shc; Neuronal Shc; Protein Rai; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SHC-transforming protein 3; SHC-transforming protein C; Shc3 p51; src homology 2 domain-containing transforming protein C3; Src homology 2 domain-containing-transforming protein C3
基因别名: N-Shc; NSHC; RAI; SHC3; SHCC
UniProt ID: (Human) Q92529, (Mouse) Q61120
Entrez Gene ID: (Human) 53358, (Rat) 114858, (Mouse) 20418
MAPK cascade
transmembrane receptor protein tyrosine kinase signaling pathway
epidermal growth factor receptor signaling pathway
Ras protein signal transduction
central nervous system development
learning or memory
synaptic transmission, glutamatergic
positive regulation of GTPase activity
intracellular signal transduction
signal transduction
