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SI-CLP detects human Stabilin-interacting chitinase like protein (SI-CLP), a novel member of the Glyco-18-domain containing protein family. SI-CLP is a secretory protein which is up-regulated in response to interleukin-4 and dexamethasone in activated macrophages. SI-CLP is also expressed by T- and B-lymphocytes, and by cells of monocytic and epithelial origin. SI-CLP is the ligand for stabilin-1, an intracellular sorting receptor which sorts SI-CLP into late endosomes and secretory lysosomes in activated macrophages.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Chitinase domain-containing protein 1; FLJ42707; MGC3234; SI-CLP; stabilin-1 interacting chitinase-like protein; Stabilin-1-interacting chitinase-like protein
基因别名: CHID1; GL008; PSEC0104; SB139; SI-CLP; SICLP
UniProt ID: (Human) Q9BWS9
Entrez Gene ID: (Human) 66005