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Abnova
SIPA1L2 Polyclonal Antibody, MaxPab™
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产品信息
H00057568-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SIPA1L2 (AAH13119.1, 1 a.a. approximately 532 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEASRHPETK WHGPPSKVLG SYKERALQKD GSCKDSPNKL SHIGDKSCSS HSSSNTLSSN TSSNSDDKHF GSGDLMDPEL LGLTYIKGAS TDSGIDTAPC MPATILGPVH LAGSRSLIHS RAEQWADAAD VSGPDDEPAK LYSVHGYASA ISAGSAAEGS MGDLSEISSH SSGSHHSGSP SAHCSKSSGS LDSSKVYIVS HSSGQQVPGS MSKPYHRQGA VNKYVIGWKK SEGSPPPEEP EVTECPGMYS EMDVMSTATQ HQTVVGDAVA ETQHVLSKED FLKLMLPDSP LVEEGRRKFS FYGNLSPRRS LYRTLSDESI CSNRRGSSFG SSRSSVLDQA LPNDILFSTT PPYHSTLPPR AHPAPSMGSL RNEFWFSDGS LSDKSKCADP GLMPLPDTAT GLDWTHLVDA ARAFEDQRVA SFCTLTDMQH GQDLEGAQEL PLCVDPGSGK EFMDTTGERS PSPLTGKVNQ LELILRQLQT DLRKEKQDKA VLQAEVQHLR QDNMRLQEES QTATAQLRKF TEWFFTTIDK KS
靶标信息
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: signal-induced proliferation-associated 1 like 2; Signal-induced proliferation-associated 1-like protein 2; SIPA1-like protein 2; SPA-1-like 2
基因别名: KIAA1389; SIPA1L2; SPAL2
UniProt ID: (Human) Q9P2F8
Entrez Gene ID: (Human) 57568
