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Invitrogen
SLC8A2 Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
产品信息
PA5-63002
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2647566
产品详细信息
Immunogen sequence: AGEDEDDGAS RIFFEPSLYH CLENCGSV
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
靶标信息
Sodium/calcium exchanger proteins are integral membrane proteins primarily seen in cardiac cells. In cardiac myocytes, the concentration of Ca2+ alternates between low levels during relaxation and high levels during contraction. The Na+/Ca2+ exchanger 1 (NCX1) protein mediates Ca2+ extrusion from cardiac cells during relaxation. Four NCX1 isoforms (NCX1.1, NCX1.3, NCX1.7, and NCX1.10) result from alternate splicing. NCX1 mRNA is present at high levels in the heart, with lower levels present in the brain. NCX2 is most abundantly expressed in brain, in contrast the the broader distribution of NCX1, which is also expressed in heart, kidney, lung, smooth and skeletal muscle. The difference in expression for the transporter subtypes is believed to reflect differences in their functional roles. Regulation mechanisms for these exchanger proteins have not been fully characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Na(+)/Ca(2+)-exchange protein 2; Na+/Ca2+-exchanging protein Nac2; sodium-calcium exchanger 2; Sodium/calcium exchanger 2; solute carrier family 8 (sodium-calcium exchanger), member 2; solute carrier family 8 (sodium/calcium exchanger), member 2; Solute carrier family 8 member 2
基因别名: KIAA1087; NCX2; SLC8A2
UniProt ID: (Human) Q9UPR5
Entrez Gene ID: (Human) 6543
