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Bethyl Laboratories
SNX1 Polyclonal Antibody
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产品信息
IHC-00433
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 475 and the C-terminus (residue 422) of Human Sorting Nexin 1.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Zebrafish, X. laevis, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig and Panda
靶标信息
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC8664; SNX1A; sorting nexin 1A; Sorting nexin-1
基因别名: HsT17379; SNX1; VPS5
UniProt ID: (Human) Q13596, (Mouse) Q9WV80
Entrez Gene ID: (Human) 6642, (Mouse) 56440
epidermal growth factor receptor binding
insulin receptor binding
protein binding
phosphatidylinositol binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
cadherin binding involved in cell-cell adhesion
transferrin receptor binding
leptin receptor binding
lipid binding
scaffold/adaptor protein
