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Immunogen sequence: EEMEKESGPG QKRPNKQEES ESPVERPLKE NPPNKMTQEK LEESSTIGQD QTLMERDTEG GAAEINCNGV IEVINYTQNS NNETLRHKED LHNANDCDVQ NLNQESSFLS SQNGDSSTSQ ETDSCTPITS EVSDTMVCQS SSTVGQSFSE QHISQLQESI RAEIPCEDEQ EQEHNGPLDN KGKSTAGNFL V; Positive Samples: 293T, HepG2, MCF7, HeLa, THP-1 ; Cellular Location: Cytoplasm, Microsome, Microsome, Nucleus, Nucleus matrix
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: OTTHUMP00000016277; Serine/arginine-rich protein-specific kinase 1; serine/arginine-rich splicing factor kinase 1; serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SR-protein-specific kinase 1; SRPK1; SRSF protein kinase 1
基因别名: SRPK1