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Invitrogen
SRSF3 Polyclonal Antibody
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图: 1 / 2
SRSF3 Antibody (PA5-101141) in ICC/IF
Immunocytochemistry analysis of SRSF3 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SRSF3 polyclonal antibody (Product # PA5-101141) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-101141
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SRSF3(Accession P84103), corresponding to amino acid residues R131-K164.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SFRS3.
靶标信息
SR proteins appear to be recruited from nuclear "speckles", in which they are concentrated, to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epididymis secretory sperm binding protein; pre-mRNA splicing factor SRp20; Pre-mRNA-splicing factor SRP20; Protein X16; RNA binding protein; Serine/arginine-rich splicing factor 3; Splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich 3 (SRp20); splicing factor, arginine/serine-rich, 20-kD; unnamed protein product
基因别名: AL024116; SFRS3; SRP20; SRSF3; X16
UniProt ID: (Human) P84103, (Mouse) P84104
Entrez Gene ID: (Human) 6428, (Mouse) 20383
regulation of alternative mRNA splicing, via spliceosome
RNA processing
mRNA processing
mRNA export from nucleus
RNA splicing
primary miRNA processing
regulation of mRNA splicing, via spliceosome
mRNA transport
cellular response to leukemia inhibitory factor
transport
insulin receptor signaling pathway
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