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FIGURE: 1 / 2
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Predicted to react with Human, Mouse, and Rat samples.
SYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp781D2042; P65; SVP65; synaptotagmin 10; Synaptotagmin X; Synaptotagmin-10; SYT; SYT-10; SytX
Gene Aliases: SYT10
UniProt ID: (Mouse) Q9R0N4, (Rat) O08625
Entrez Gene ID: (Mouse) 54526, (Rat) 60567
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