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The recommended shelf life for this product is 1 year from date of receipt.
The p70 S6 kinase (p70 Ribosomal Protein S6 Kinase, p70S6K) is a 70 kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. p70 S6 kinase is predominantly localized in the cytoplasm, and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response, and tissue repair. p70 S6 kinase acts downstream of phosphoinositide (PI) 3-kinase, and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis. The kinase activity of p70 S6 kinase leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding p70 S6 kinase and overexpression are seen in some breast cancer cell lines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC104346; MGC2553; Selenoprotein S; SelS; valosin-containing protein-interacting membrane protein; VCP-interacting membrane protein; VCP-interacting membrane selenoprotein
基因别名: AD-015; SBBI8; SELENOS; SELS; VIMP