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Invitrogen
Substance P Recombinant Rabbit Monoclonal Antibody (K01_4N39)
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产品信息
MA567454
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K01_4N39
抗原
A synthesized peptide derived from human Substance P.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA, 150mM NaCl, 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Substance P (SP) is currently thought to be one of the most important neurotransmitters and neurotransmitters in the brain. It is an undecapeptide belonging to the tachykinin family, which consists of excitatory neuropeptides synthesised in neuronal and glial cells of the human central and peripheral nervous system. Substance P, Neurokinin A, Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavage of the precursor Protachykinin-1. Substance P forms the major endogenous ligand for Neurokinin 1 Receptor. The pharmacology of Substance P has been associated with a number of neurological and psychiatric disorders, namely nociception, migraine, asthma, nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. It has also been linked to obesity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC26719; neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; neuropeptide gamma; neuropeptide K; PPT; precursor 1; preprotachykinin; protachykinin; Protachykinin-1; RAT TAC; substance K; substance P; TAC1; tachykinin 2; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
基因别名: Hs.2563; NK2; NKA; NKNA; NPK; TAC1; TAC2
UniProt ID: (Human) P20366
Entrez Gene ID: (Human) 6863
response to yeast
positive regulation of acute inflammatory response
negative regulation of systemic arterial blood pressure
inflammatory response
positive regulation of cytosolic calcium ion concentration
tachykinin receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
chemical synaptic transmission
insemination
long-term memory
regulation of blood pressure
associative learning
detection of abiotic stimulus
response to hormone
negative regulation of heart rate
positive regulation of epithelial cell migration
sensory perception of pain
antibacterial humoral response
antifungal humoral response
killing of cells of other organism
positive regulation of synaptic transmission, cholinergic
positive regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
innate immune response
positive regulation of action potential
positive regulation of ossification
response to pain
positive regulation of lymphocyte proliferation
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
detection of temperature stimulus involved in sensory perception of pain
positive regulation of stress fiber assembly
regulation of sensory perception of pain
antimicrobial humoral immune response mediated by antimicrobial peptide
positive regulation of sperm motility
positive regulation of sensory perception of pain
cellular response to nerve growth factor stimulus
positive regulation of corticosterone secretion
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