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For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Sutimlimab is an anti-C1s antibody. Studies have shown that it can significantly increase hemoglobin levels in patients with primary cold agglutinin disease. Cold agglutinin disease (CAD) is a type of acquired autoimmune hemolytic anemia (AIHA). In cold environments, cold parts of the body will have clinical symptoms related to red blood cell aggregation (for example, the Internet Plaque or cyanosis) and hemolytic anemia.
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