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Invitrogen
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Immunogen sequence: MEKGMSSGEG LPSRSSQVSA GKITAKELET KQSYKEKRGG FVLVHAGAGY HSESKAKEYK HVCKRACQKA IEKLQAGALA TDAVTAALV
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%.
This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ20212; MGC39159; Taspase-1; Threonine aspartase 1
基因别名: C20orf13; dJ585I14.2; TASP1
UniProt ID: (Human) Q9H6P5
Entrez Gene ID: (Human) 55617