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Invitrogen
TCEA1 Polyclonal Antibody
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TCEA1 Antibody (PA5-87971) in WB
Western blot analysis of TCEA1 in extracts of various cell lines. Samples were incubated with TCEA1 Polyclonal antibody (Product # PA5-87971) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
产品信息
PA5-87971
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 75-140 of human TCEA1 (NP_0067471)
偶联物
形式
Liquid
浓度
1.51 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KLLDGPSTEK DLDEKKKEPA ITSQNSPEAR EESTSSGNVS NRKDETNARD TYVSSFPRAP STSDSV
Positive Samples: U-87MG, 293T, Mouse kidney; Cellular Location: Nucleus
靶标信息
TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: transcription elongation factor A (SII), 1; Transcription elongation factor A protein 1; Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.o; transcription factor IIS
基因别名: GTF2S; SII; TCEA; TCEA1; TF2S; TFIIS
UniProt ID: (Human) P23193
Entrez Gene ID: (Human) 6917
transcription-coupled nucleotide-excision repair
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
regulation of DNA-templated transcription, elongation
positive regulation of exoribonuclease activity
