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This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Nuclear factor SPBP; Protein AR1; SPRE-binding protein; stromelysin 1 PDGF responsive element binding protein; stromelysin 1 PDGF-responsive element-binding protein; stromelysin PDGF responsive element binding protein transcription factor; Stromelysin-1 PDGF-responsive element-binding protein; stromelysin-1 platelet-derived growth factor-responsive element binding protein; TCF-20; Transcription factor 20; transcription factor 20 (AR1)
基因别名: 2810438H08Rik; AR1; KIAA0292; mKIAA0292; SPBP; TCF-20; TCF20
UniProt ID: (Human) Q9UGU0, (Mouse) Q9EPQ8
Entrez Gene ID: (Human) 6942, (Rat) 366964, (Mouse) 21411