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Positive test controls include: SW480, MCF7, A-549, U-251MG, Mouse kidney, Mouse lung. The target is usually found in the following locations: Secreted.
Immunogen sequence: EMCEIPEMDS HLVEKLGQHL LPWMDRLSLE HLNPSIYVGL RLSSLQAGTK EDLYLHSLKL GYQQCLLGSA FSEDDGDCQG KPSMGQLALY LLALRANWHD HKGHPHTSYY QYGLGILALC LHQKRVHDSV VDKLLYAVEP FHQGHHSVDT AAMAGLAFTC LKRSNFNPGR RQRITMAIRT VREEILKAQT PEGHFGNVYS TPLALQFLMT SPMRGAELGT ACLKARVALL AS
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: macrocytic anemia; TC II; TC TC D22S676; TC-2; TCII; Transcobalamin II; transcobalamin II; macrocytic anemia; Transcobalamin-2; vitamin B12-binding protein 2
基因别名: AW208754; D22S676; D22S750; II; TC; TC II; TC-2; TC2; TCII; Tcn-2; TCN2
UniProt ID: (Human) P20062, (Mouse) O88968
Entrez Gene ID: (Human) 6948, (Mouse) 21452