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Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hITF; hP1.B; Intestinal trefoil factor; mITF; Polypeptide P1.B; rITF; rP1.B; Trefoil factor 3; trefoil factor 3 (intestinal)
基因别名: ITF; mITF; P1B; TFF3; TFI
UniProt ID: (Human) Q07654, (Mouse) Q62395, (Rat) Q03191
Entrez Gene ID: (Human) 7033, (Mouse) 21786, (Rat) 25563