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Bethyl Laboratories
TIA-1 Polyclonal Antibody
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TIA-1 Antibody (A303-990A) in WB
Detection of human and mouse TIA-1 by western blot. Samples: Whole cell lysate from HeLa (15 µg), HEK293T (15 µg), Jurkat (15 µg), mouse TCMK-1 (50 µg), and mouse NIH 3T3 (50 µg) cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-TIA-1 antibody (Product # A303-990A) (lot A303-990A-2) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
A303-990A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1 to 50 of Human TIA1 Cytotoxic Granule-Associated RNA Binding Protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: nucleolysin TIA-1; p40 TIA 1; p40-TIA-1 (containing p15-TIA-1); RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA 1; TIA1 protein; TIAL1; TIAR; unnamed protein product
基因别名: 2310050N03Rik; ALS26; mTIA-1; TIA-1; WDM
UniProt ID: (Human) P31483, (Mouse) P52912
Entrez Gene ID: (Human) 7072, (Mouse) 21841
regulation of alternative mRNA splicing, via spliceosome
negative regulation of cytokine production
negative regulation of translation
stress granule assembly
regulation of mRNA splicing, via spliceosome
protein localization to cytoplasmic stress granule
positive regulation of epithelial cell apoptotic process
apoptotic process
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