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Invitrogen
TIAM1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-80130
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human TIAM1 (1518-1554aa ASVDRDLQERLQATSISQRERGRKTLDSHASRMAQLK).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: MCF-7 whole cell.
靶标信息
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: human T-lymphoma invasion and metastasis inducing TIAM1 protein; Rho guanine nucleotide exchange factor TIAM1; T cell lymphoma invasion and metastasis 1; T-lymphoma invasion and metastasis-inducing protein 1; TIAM-1
基因别名: NEDLDS; TIAM-1; TIAM1
UniProt ID: (Human) Q13009
Entrez Gene ID: (Human) 7074
cell-matrix adhesion
signal transduction
small GTPase mediated signal transduction
positive regulation of cell proliferation
regulation of epithelial to mesenchymal transition
positive regulation of epithelial to mesenchymal transition
cell migration
Rac protein signal transduction
positive regulation of cell migration
intracellular signal transduction
non-canonical Wnt signaling pathway
ephrin receptor signaling pathway
positive regulation of axonogenesis
regulation of small GTPase mediated signal transduction
Wnt signaling pathway, planar cell polarity pathway
protein-containing complex assembly
regulation of dopaminergic neuron differentiation
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