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Invitrogen
TLE4 Polyclonal Antibody
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TLE4 Antibody (PA5-30192) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of TLE4 was performed in DIV10 rat E18 primary cortical neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: TLE4 Polyclonal Antibody (Product # PA5-30192) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
产品信息
PA5-30192
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human TLE4. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.95 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: NT2D1, IMR32, Jurkat, HeLa.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Chicken (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B lymphocyte gene 1; enhancer of split groucho 4; Grg-4; Groucho-related protein 4; Protein ESP2; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4, E(spl) homolog; transducin-like enhancer of split 4, homolog of Drosophila E(sp1); transducin-like enhancer of split 4, homolog of Drosophila E(spl); Transducin-like enhancer protein 4
基因别名: BCE-1; BCE1; E(spI); ESG; ESG4; Esp2; Grg-4; GRG4; KIAA1261; TLE4
UniProt ID: (Human) Q04727, (Rat) Q07141
Entrez Gene ID: (Human) 7091, (Rat) 25565
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
biological_process
Wnt signaling pathway
beta-catenin-TCF complex assembly
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
negative regulation of nucleic acid-templated transcription
