Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
TMEM43 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
TMEM43 Antibody (PA5-110497) in WB
Western blot analysis of TMEM43 in extracts of various cell lines. Samples were incubated with TMEM43 Polyclonal antibody (Product # PA5-110497) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 5s.
产品信息
PA5-110497
产品规格
种属反应
Human,
Mouse
已发表种属
Fruit fly
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VAPENEGRLV HIIGALRTSK LLSDPNYGVH LPAVKLRRHV EMYQWVETEE SREYTEDGQV KKETRYSYNT EWRSEIINSK NFDREIGHKN PSAMAVESFM ATAPFVQIGR FFLSSGLIDK VDNFKSLSLS KLEDPHVDII RRGDFFYHSE NPKYPEVGDL RVSFSYAGLS GDDPDLGPAH VVTVIARQRG DQLVPFSTKS GDTLLLLHHG DFSAEEVFHR ELRSNSMKTW G
靶标信息
This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein LUMA; Transmembrane protein 43
基因别名: 1200015A22Rik; ARVC5; ARVD5; EDMD7; LUMA; TMEM43; UNQ2564/PRO6244
UniProt ID: (Human) Q9BTV4, (Mouse) Q9DBS1
Entrez Gene ID: (Human) 79188, (Mouse) 74122
