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Invitrogen
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Immunogen sequence: KYEAAKKWNLP AVTIAWLLET ARTGKRADES HFLIENSTKE ERSLETEITN GINLNSDTAE HPGTRLQTHR KTVVTPLDMN RFQSKAFRAV VS
Highest antigen sequence identity to the following orthologs - mouse 68%, rat 66%.
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; DNA topoisomerase II-binding protein 1; TOPBP 1; TopBP1
基因别名: KIAA0259; TOP2BP1; TOPBP1
UniProt ID: (Human) Q92547
Entrez Gene ID: (Human) 11073