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Invitrogen
TOR1AIP2 Polyclonal Antibody
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产品信息
PA5-67110
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SGLREPQEDSQ KDLENDPSVN SQAQETTIIA SNAEEAEILH SACGLSKDHQ EVETEGPESA DTGDKSESPD EANVGK
Highest antigen sequence identity to the following orthologs - mouse 48%, rat 52%.
靶标信息
One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 15 kDa interferon-responsive protein; IFRG15; interferon responsive gene 15; lumenal domain like LAP1; Lumenal domain-like LAP1; RP11-12M5.5; torsin A interacting protein 2; Torsin-1A-interacting protein 2; Torsin-1A-interacting protein 2, isoform IFRG15
基因别名: IFRG15; LULL1; NET9; TOR1AIP2
UniProt ID: (Human) Q9H496
Entrez Gene ID: (Human) 163590
