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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total TP53I11 protein.
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: p53-induced gene 11 protein; transformation related protein 53 inducible protein 11; Tumor protein p53-inducible protein 11; unnamed protein product
基因别名: PIG11; TP53I11; Trp53i11
UniProt ID: (Human) O14683, (Rat) B3DMA0
Entrez Gene ID: (Human) 9537, (Rat) 311209