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Invitrogen
TPM3 Polyclonal Antibody
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TPM3 Antibody (720306) in ICC/IF
For immunofluorescence analysis, C2C12 cells were fixed and permeabilized for detection of endogenous Tropomyosin-3 using Anti-TPM-3 Rabbit Polyclonal Antibody (Product # 720306, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of TPM-3 protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). ... View More
产品信息
720306
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptides corresponding to Human TPM3 (aa 40-49, 225-234)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 0.1% BSA, 30% glycerol
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Horse, Rat and Pig
靶标信息
TPM3 (tropomyosin 3) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha-tropomyosin, slow skeletal; cytoskeletal tropomyosin TM30; epididymis luminal protein 189; epididymis secretory sperm binding protein Li 82p; Gamma-tropomyosin; heat-stable cytoskeletal protein 30 kDa; hTM5; nonmuscle tropomyosin 5; skalphaTM.2; tropomyosin; tropomyosin 3, gamma; tropomyosin 5; Tropomyosin alpha-3 chain; tropomyosin gamma; tropomyosin non-muscle; Tropomyosin-3; Tropomyosin-5
基因别名: CAPM1; CFTD; gamma-TM; HEL-189; HEL-S-82p; hscp30; hTM30nm; hTMnm; NEM1; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TM5; Tm5NM; TMnm; Tpm-5; TPM3; Tpm5; TPMsk3; TRK; Trop-5
UniProt ID: (Human) P06753, (Rat) Q63610, (Mouse) P21107
Entrez Gene ID: (Human) 7170, (Rat) 117557, (Mouse) 59069
