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Recommended positive controls: 293T.
Predicted reactivity: Mouse (100%), Rat (99%), Zebrafish (83%), Dog (93%), Pig (100%), Chicken (84%), Rhesus Monkey (93%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
TPM3 (tropomyosin 3) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha-tropomyosin, slow skeletal; cytoskeletal tropomyosin TM30; epididymis luminal protein 189; epididymis secretory sperm binding protein Li 82p; Gamma-tropomyosin; heat-stable cytoskeletal protein 30 kDa; hTM5; tropomyosin; Tropomyosin alpha-3 chain; tropomyosin gamma; Tropomyosin-3; Tropomyosin-5
基因别名: CAPM1; CFTD; HEL-189; HEL-S-82p; hscp30; NEM1; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TM5; TPM3; TPMsk3; TRK
UniProt ID: (Human) P06753
Entrez Gene ID: (Human) 7170