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Rockland
TRBP1 Polyclonal Antibody
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TRBP1 Antibody (600-401-FN2) in WB
Western Blot of TRBP1 antibody. Lane A: 3T3 Cell lysate at 1 µg/mL . Lane B: 3T3 Cell lysate at 2 µg/mL. Load: 35 µg per lane. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 64.4 kDa, ~179 kDa for TRBP1. Other band(s): TRBP1 splice variants and isoforms.
产品信息
600-401-FN2
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-TRBP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide from near the internal region of human TRBP1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Probable methyltransferase TARBP1; RP5-827C21.5; TAR (HIV) RNA binding protein 1; TAR (HIV) RNA-binding protein 1; TAR (HIV-1) RNA binding protein 1; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; tRNA methyltransferase 3 homolog; TRP-185
基因别名: Gm179; TARBP1; TRM3; TRP-185; TRP185
UniProt ID: (Human) Q13395
Entrez Gene ID: (Mouse) 212728, (Human) 6894
