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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
A suggested positive control is NIH-3T3 cell lysate.
PA5-20331 can be used with blocking peptide PEP-0451.
The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: probable methyltransferase TARBP1; RP5-827C21.5; TAR (HIV-1) RNA binding protein 1; TAR RNA-binding protein 1; tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1
基因别名: Gm179; Tarbp1
UniProt ID: (Mouse) E9Q368
Entrez Gene ID: (Mouse) 212728