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Invitrogen
TRPC3 Polyclonal Antibody
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产品信息
PA5-20258
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 14 amino acid peptide from near the carboxy terminus of human TRPC3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is human brain tissue lysate.
PA5-20258 can be used with blocking peptide PEP-0394.
靶标信息
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hTrp-3; hTrp3; mTrp3; Receptor-activated cation channel TRP3; Short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor potential cation channel, subfamily C, member 3; Transient receptor protein 3; TRP-3; Trp-related protein 3; TrpC3
基因别名: Mwk; SCA41; Trcp3; TRP3; TRPC3; Trrp3
UniProt ID: (Human) Q13507, (Mouse) Q9QZC1
Entrez Gene ID: (Human) 7222, (Mouse) 22065
calcium ion transport
manganese ion transport
single fertilization
phototransduction
positive regulation of calcium ion transport into cytosol
platelet activation
response to ATP
response to calcium ion
calcium ion transmembrane transport
positive regulation of cardiac muscle hypertrophy in response to stress
transport
ion transport
regulation of cytosolic calcium ion concentration
transmembrane transport
