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Invitrogen
TSPAN8 Polyclonal Antibody
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TSPAN8 Antibody (PA5-89125) in WB
Western blot analysis of TSPAN8 in extracts of various cell lines. Samples were incubated with TSPAN8 Polyclonal antibody (Product # PA5-89125) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-89125
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 110-200 of human TSPAN8 (NP_0046071)
偶联物
形式
Liquid
浓度
3.96 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KSKSDRIVNE TLYENTKLLS ATGESEKQFQ EAIIVFQEEF KCCGLVNGAA DWGNNFQHYP ELCACLDKQR PCQSYNGKQV YKETCISFIK D; Positive Samples: Mouse lung, Rat lung; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein that belongs to the tetraspanin family of transmembrane proteins and is thought to play a role in signal transduction events that influence cell development, activation, growth and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal and pancreatic cancers, strongly suggesting a role in cancer formation and metastasis. The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: D6.1A; Tetraspanin-8; Tetraspanin8; transmembrane 4 superfamily member 3; Tspan-8
基因别名: C76990; CO-29; E330007O21Rik; Tm4sf3; Tspan8
UniProt ID: (Mouse) Q8R3G9
Entrez Gene ID: (Rat) 171048, (Mouse) 216350
