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Invitrogen
Tartrate Resistant Acid Phosphatase Monoclonal Antibody (5C5E7)
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产品信息
MA5-38435
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5C5E7
抗原
Purified recombinant fragment of human ACP5 (aa: 221-325) expressed in E. Coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody has been tested in indirect ELISA.
靶标信息
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen and liver. Its expression is increased in spleen and monocytes of patients with Gaucher's disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin's lymphoma and in the sera of patients undergoing active bone turnover.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: human purple acid phosphatase; Tartrate-resistant acid ATPase; tartrate-resistant acid phosphatase 5a; tartrate-resistant acid phosphatase 5b; Tartrate-resistant acid phosphatase type 5; TR-AP; TRAPase; TrATPase; Type 5 acid phosphatase
基因别名: ACP5; HPAP; TRACP5a; TRACP5b; TRAP; TrATPase
UniProt ID: (Human) P13686
Entrez Gene ID: (Human) 54
ossification
riboflavin metabolic process
negative regulation of cell adhesion
response to zinc ion
dephosphorylation
osteoclast differentiation
positive regulation of cell migration
response to lipopolysaccharide
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
negative regulation of tumor necrosis factor production
negative regulation of superoxide anion generation
multicellular organismal response to stress
response to L-ascorbic acid
response to cytokine
negative regulation of nitric oxide biosynthetic process
bone resorption
negative regulation of inflammatory response
defense response to Gram-positive bacterium
bone morphogenesis
response to cholesterol
