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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: FPRACVSSKN LMEKECCPPW SGDRSPCGQL SGRGSCQNIL LSNAPLGPQF PFTGVDDRES W
Highest antigen sequence indentity to the following orthologs: Rat - 85%, Mouse - 85%.
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: LB24-AB; monophenol monooxygenase; oculocutaneous albinism IA; SK29-AB; tumor rejection antigen AB; tyrosinase; tyrosinase precursor (EC 1.14.18.1)
基因别名: ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
UniProt ID: (Human) P14679
Entrez Gene ID: (Human) 7299