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NeoBiotechnologies
Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Recombinant Mouse Monoclonal Antibody (rG3E6)
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Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Antibody (7306-MSM22-P1) in IHC (P)
Formalin-fixed, paraffin-embedded human skin stained with Tyrosinase Related Protein (TRP-1) Recombinant Mouse Monoclonal Antibody (rG3E6). Inset: PBS instead of primary antibody; secondary only negative control.
产品信息
7306-MSM22-P1
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
rG3E6
抗原
Prokaryotic recombinant fusion protein corresponding to the C-terminus of the TRP-1 molecule.
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product cellular localization: Nucleus.
Positive control: Breast: A strong TRPS1 staining should be seen in luminal breast epithelial cells. (For low-level TRPS1 detection: Testis: A weak nuclear TRPS1 staining should be seen in spermatogonia.).
Tissue specificity: Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells.
靶标信息
This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5,6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; DHICA oxidase; Glycoprotein 75; Melanoma antigen gp75; MGC120175; MGC149362; RP11-3L8.1; TRP; TRY1; TRY4; TRYP1; Tyrosinase-related protein 1
基因别名: b-PROTEIN; CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP; TYRP1; TYRRP
UniProt ID: (Human) P17643
Entrez Gene ID: (Human) 7306
