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Invitrogen
UBL4A Polyclonal Antibody
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UBL4A Antibody (PA5-92164) in WB
Western blot analysis of UBL4A in extracts of various cell lines. Samples were incubated with UBL4A Polyclonal antibody (Product # PA5-92164) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-92164
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-157 of human UBL4A (NP_0550501)
偶联物
形式
Liquid
浓度
0.11 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MQLTVKALQG RECSLQVPED ELVSTLKQLV SEKLNVPVRQ QRLLFKGKAL ADGKRLSDYS IGPNSKLNLV VKPLEKVLLE EGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQLQ RDYERSLSRL TLDDIERLAS RFLHPEVTET MEKGFSK; Positive Samples: U-87MG, A-549, HeLa, Jurkat, Mouse liver, Mouse brain, Mouse heart, Mouse kidney; Cellular Location: Cytoplasm, cytosol
靶标信息
UBL4A is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. UBL4A is the TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: housekeeping protein DXS254E; ubiquitin-like 4; ubiquitin-like 4A; Ubiquitin-like protein 4A; Ubiquitin-like protein GDX
基因别名: DX254E; DXHXS254E; DXS254E; DXS254Eh; G6PD; GDX; GET5; MDY2; RGD1563983; TMA24; UBL4; UBL4A
UniProt ID: (Human) P11441, (Mouse) P21126, (Rat) B2GV38
Entrez Gene ID: (Human) 8266, (Mouse) 27643, (Rat) 293864
